review article 
Activation of aminocyclopropanes via radical intermediates
 August 8, 2022 
Aminocyclopropanes are versatile building blocks for accessing high value-added nitrogen-containing products. To control ring-opening promoted by ring strain, the Lewis acid activation of donor-acceptor substituted systems is now well established. Over the last decade, alternative approaches have emerged proceeding via the formation of radical intermediates, alleviating the need for double activation of the cyclopropanes. This tutorial review summarizes key concepts and recent progress in ring-opening transformations of aminocyclopropanes via radical intermediates, divided into formal cycloadditions and 1,3-difunctionalizations.
Type
 review article 
Web of Science ID
WOS:000837423900001
Author(s)
Date Issued
2022-08-08
Publisher
Published in
Volume
51
Start page
7344
End page
7357
Editorial or Peer reviewed
REVIEWED
Written at
EPFL
EPFL units
Available on Infoscience
 August 29, 2022 
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