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research article

Feedback topology and XOR-dynamics in Boolean networks with varying input structure

Ciandrini, L.
•
Maffi, C.  
•
Motta, A.
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2009
Physical Review E

We analyze a model of fixed in-degree random Boolean networks in which the fraction of input-receiving nodes is controlled by the parameter gamma. We investigate analytically and numerically the dynamics of graphs under a parallel XOR updating scheme. This scheme is interesting because it is accessible analytically and its phenomenology is at the same time under control and as rich as the one of general Boolean networks. We give analytical formulas for the dynamics on general graphs, showing that with a XOR-type evolution rule, dynamic features are direct consequences of the topological feedback structure, in analogy with the role of relevant components in Kauffman networks. Considering graphs with fixed in-degree, we characterize analytically and numerically the feedback regions using graph decimation algorithms (Leaf Removal). With varying gamma, this graph ensemble shows a phase transition that separates a treelike graph region from one in which feedback components emerge. Networks near the transition point have feedback components made of disjoint loops, in which each node has exactly one incoming and one outgoing link. Using this fact, we provide analytical estimates of the maximum period starting from topological considerations.

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Type
research article
DOI
10.1103/PhysRevE.80.026122
Web of Science ID

WOS:000269637900032

Author(s)
Ciandrini, L.
Maffi, C.  
Motta, A.
Bassetti, B.
Cosentino Lagomarsino, M.
Date Issued

2009

Published in
Physical Review E
Volume

80

Issue

2

Article Number

026122

Subjects

Boolean algebra

•

cellular biophysics

•

feedback

•

genetics

•

molecular biophysics

•

random processes

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Transcriptional Regulatory Networks

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Kauffman Networks

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Random Graphs

•

Biology

•

Models

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LBS  
Available on Infoscience
April 10, 2011
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/66078
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