review article
Receptors of anthrax toxin and cell entry
Anthrax toxin-receptor interactions are critical for toxin delivery to the host cell cytoplasm. This review summarizes what is known about the molecular details of the protective antigen (PA) toxin subunit interaction with either the ANTXR1 and ANTXR2 cellular receptors, and how receptor-type can dictate the low pH threshold of PA pore formation. The roles played by cellular factors in regulating the endocytosis of toxin-receptor complexes is also discussed.
Type
review article
Web of Science ID
WOS:000272755000008
Author(s)
Young, John A. T.
Date Issued
2009
Publisher
Published in
Volume
30
Issue
6
Start page
406
End page
12
Editorial or Peer reviewed
NON-REVIEWED
Written at
EPFL
EPFL units
Available on Infoscience
July 29, 2010
Use this identifier to reference this record