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research article

Robot-Assisted Measurement of the Critical Micelle Concentration

Scamarcio, Vincenzo  
•
Slor, Gadi  
•
Hughes, Josie  
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January 28, 2025
Advanced Intelligent Systems

The critical micelle concentration (CMC) is the key characterization of surfactants. To date, no method can yield sequential CMC measurements in an automated fashion. This work introduces SIMO (smart integrator for manual operations), a novel robotic platform for automating the determination of CMC for surfactants. It highlights the precision and reproducibility of SIMO, with an 80% reduction in standard deviation compared to a manual method. The article discusses the robotic protocol and data postprocessing, highlighting the challenges behind integrating automation and robotics in laboratories. SIMO's reliability is tested against a challenging experiment, that of determining the effect of various cations on the CMC of polymeric surfactants. The work presented showcases the potential of robotics in scientific experimentation, promising enhanced accuracy and efficiency.

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Type
research article
DOI
10.1002/aisy.202400386
Web of Science ID

WOS:001406847900001

Author(s)
Scamarcio, Vincenzo  

École Polytechnique Fédérale de Lausanne

Slor, Gadi  

École Polytechnique Fédérale de Lausanne

Hughes, Josie  

École Polytechnique Fédérale de Lausanne

Stellacci, Francesco  

École Polytechnique Fédérale de Lausanne

Date Issued

2025-01-28

Publisher

WILEY

Published in
Advanced Intelligent Systems
Subjects

amphiphiles

•

automation

•

critical micelle concentration

•

micelles

•

robot manipulation

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
SUNMIL  
CREATE-LAB  
FunderFunding(s)Grant NumberGrant URL

European Research Council (ERC)

European Research Council (ERC)

Available on Infoscience
February 6, 2025
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/246581
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