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research article
New efficient synthesis of long chain di- and tri-aminopolyols
The asymmetric synthesis of long chain di- and tri-amino polyols is reported. The developed methodology is based on the functionalization of 3,3'-methylenebis{[6-(benzyloxy)methoxy]cyclohept-3-en-1-ol} derivatives that allows the selective introduction of amine moieties on defined positions of polyketide fragments. The versatile strategy disclosed here requires few purification steps and may generate a large panel of stereoisomers.
Use this identifier to reference this record
Type
research article
Web of Science ID
WOS:000240425300012
Publication date
2006
Published in
Issue
17
Start page
3903
End page
3909
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
May 15, 2006