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research article

A method for determining neural connectivity and inferring the underlying network dynamics using extracellular spike recordings

Makarov, V. A.
•
Panetsos, F.
•
De Feo, O.  
2005
Journal of Neuroscience Methods

In the present paper we propose a novel method for the identification and modeling of neural networks using extracellular spike recordings. We create a deterministic model of the effective network, whose dynamic behavior fits experimental data. The network obtained by our method includes explicit mathematical models of each of the spiking neurons and a description of the effective connectivity between them. Such a model allows us to study the properties of the neuron ensemble independently from the original data. It also permits to infer properties of the ensemble that cannot be directly obtained from the observed spike trains. The performance of the method is tested with spike trains artificially generated by a number of different neural networks.

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Type
research article
DOI
10.1016/j.jneumeth.2004.11.013
Web of Science ID

WOS:000229704000016

Author(s)
Makarov, V. A.
Panetsos, F.
De Feo, O.  
Date Issued

2005

Published in
Journal of Neuroscience Methods
Volume

144

Issue

2

Start page

265

End page

279

Subjects

Neural circuits

•

Spike trains

•

Connectivity identification

•

Network modeling

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LANOS  
Available on Infoscience
April 29, 2005
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/213307
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