This chapter examines a contemporary manifestation of G. B. Goode’s conjecture as a possible framework for successful alliances between universities and the cultural galleries, libraries, archives and museums (GLAMs) sector. It considers the mutually beneficial museum–university partnership DomeLab in the context of literature on academic and GLAM collaboration. The chapter focuses the discussion on the development of state-of-the-art fulldome infrastructure as a shared framework across all partners with numerous applied outcomes and lasting impacts. DomeLab is an immersive, dome-based video projection environment six-metres wide, horizontally suspended over users and filled with interactive real-time or pre-rendered content. Domelab demonstrates commercial value for research and creative industries related to content production, with an increasing number of creative industry groups taking up content production for clients of DomeLab. DomeLab demonstrates educational value by providing new models of immersive pedagogy and technological value by pioneering software pipelines and creating unique hardware integration knowledge, valuable to the fulldome community worldwide.