A functionally characterized test set of human induced pluripotent stem cells
Previous work has suggested that induced pluripotent stem cells (iPSCs) are inferior to embryonic stem cells (ESCs) with respect to in vitro differentiation, raising questions about the utility of iPSCs for disease modeling. Characterization of a test set of 16 human iPSC lines shows that they perform as well as ESCs in differentiating to motor neurons.
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Boulting, G. L., Kiskinis, E., Croft, G. F., Amoroso, M. W., Oakley, D. H., Wainger, B. J., Williams, D. J., Kahler, D. J., Yamaki, M., Davidow, L., Rodolfa, C. T., Dimos, J. T., Mikkilineni, S., MacDermott, A. B., Woolf, C. J., Henderson, C. E., Wichterle, H., & Eggan, K. (2011). A functionally characterized test set of human induced pluripotent stem cells. Nature Biotechnology, 29(3), 279–286. https://doi.org/10.1038/nbt.1783
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2011-03-01
29
3
279
286
REVIEWED
OTHER