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research article
Rhodium(III)-Catalyzed Cyclopropane C-H/C-C Activation Sequence Provides Diastereoselective Access to alpha-Alkoxylated gamma-Lactams
July 2, 2020
A Cp*Rh(III)-catalyzed C-H/C-C bond activation sequence of cyclopropyl hydroxamates has been developed. The three-component process allows trapping of the intermediate rhodacycle with diazomalonates and an alcohol nucleophile to provide access to synthetically valuable alpha-alkoxylated gamma-lactams with trans diastereoselectivity.
Type
research article
Web of Science ID
WOS:000547468700023
Authors
Publication date
2020-07-02
Publisher
Published in
Volume
22
Issue
13
Start page
5030
End page
5034
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
July 29, 2020
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