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  4. Endocrine Disrupting Compounds Affecting Corticosteroid Signaling Pathways in Czech and Swiss Waters: Potential Impact on Fish
 
research article

Endocrine Disrupting Compounds Affecting Corticosteroid Signaling Pathways in Czech and Swiss Waters: Potential Impact on Fish

Macikova, Petra
•
Groh, Ksenia J.
•
Ammann, Adrian A.
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2014
Environmental Science & Technology

This study investigated the occurrence of corticosteroid signaling disruptors in wastewaters and rivers in the Czech Republic and in Switzerland. 36 target compounds were detected using HPLC-MS/MS, with up to 6.4 mu g/L for azole antifungals that indirectly affect corticosteroid signaling. Glucocorticoid receptor (GR)-mediated activity was determined using the GR-CALUX bioassay with dexamethasone equivalent concentrations ranging from

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Type
research article
DOI
10.1021/es502711c
Web of Science ID

WOS:000344449100051

Author(s)
Macikova, Petra
Groh, Ksenia J.
Ammann, Adrian A.
Schirmer, Kristin  
Suter, Marc J. -F.
Date Issued

2014

Publisher

Amer Chemical Soc

Published in
Environmental Science & Technology
Volume

48

Issue

21

Start page

12902

End page

12911

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
TOX  
Available on Infoscience
December 30, 2014
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/109702
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