In order to optimize the load-bearing behavior of sandwich structures and adapt it to specific requirements, their core may be composed of layers of different materials with tailored properties. These layers may consist not only of soft foam or honeycomb materials but also comprise stiff materials, e.g. timber, or even very stiff laminates in the case of fiber-reinforced polymer (FRP) materials. In this paper, new analytical models for predicting axial and shear stresses in multilayer sandwich structures composed of stiff core layers and intermediate laminates are presented. The models are based on new formulations for calculating the bending and shear stiffness of multilayer sandwiches. They have been validated by finite element modeling (FEM) and the results from four-point bending experiments on GFRP-balsa sandwich beams with complex core assembly. In contrast to existing models, e.g. the high-order sandwich panel theory (HSAPT), the new models are able to accurately predict axial and shear stresses in stiff cores and intermediate FRP laminate layers. (C) 2014 Elsevier Ltd. All rights reserved.