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patent

Novel cathepsin inhibitors

Oricchio, Elisa  
•
Petruzzella, Aaron Simone  
•
Correia, Bruno  
2023

The present invention relates to a cathepsin inhibitor comprising or consisting of Formula (I) (X1)(X2)(X3)(X4)(Y)(X5)(X6)(X7) wherein (X1) is an amino acid selected from K, L, F and M; (X2) is an amino acid selected from L, A, D, E, F, G, H, I, K, M, N, S, W, Y, Q and R; (X3) is an amino acid selected from R, A and L; (X4) is an amino acid selected from M, I, K, V and Y; (X5) is an amino acid selected from P, A, I, L, V, W and Y; (X6) is an amino acid selected from K, A, E, F, G, I, L, M, N, Q, S, T, V, W, Y and Q; (X7) is an amino acid selected from D, A, E, F, G, I, L, M, N, P, T, V, W, Y, Q and R; and (Y) is a Michael acceptor.

  • Details
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Type
patent
EPO Family ID

77750041

Author(s)
Oricchio, Elisa  
Petruzzella, Aaron Simone  
Correia, Bruno  
Note

Alternative title(s) : (de) Neue cathepsinhemmer (fr) Nouveaux inhibiteurs de la cathepsine

TTO classification

TTO:6.2183

EPFL units
AVP-R-TTO  
IdentifierCountry codeKind codeDate issued

EP4387981

EP

A1

2024-06-26

CN118139871

CN

A

2024-06-04

AU2022331815

AU

A1

2024-03-07

CA3229302

CA

A1

2023-02-23

WO2023021190

WO

A1

2023-02-23

EP4137503

EP

A1

2023-02-22

Available on Infoscience
March 2, 2023
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/195348
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