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research article

Subthreshold cross-correlations between cortical neurons: A reference model with static synapses

Melamed, O.  
•
Silberberg, G.  
•
Markram, H.  
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2005
NEUROCOMPUTING

The structure of cross-correlations between subthreshold potentials of neocortical neurons was recently examined. Characteristic features included broad widths and significant peak advances. It was suggested that dynamic synapses shape these cross-correlations. Here a reference model is developed comprising leaky integrators with static synapses. The forms of the subthreshold correlations are derived analytically for two different forms of synaptic input: steady drive and populations bursts. For the latter case the model captures the widths seen in experiment. However, the model could not account for the peak advance. It is concluded that models with static synapses lack the necessary biological details for describing cortical dynamics.

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Type
research article
DOI
10.1016/j.neucom.2004.10.098
Web of Science ID

WOS:000229663600089

Author(s)
Melamed, O.  
Silberberg, G.  
Markram, H.  
Gerstner, W.  
Richardson, M. J. E.
Date Issued

2005

Publisher

Elsevier

Published in
NEUROCOMPUTING
Issue

65-66

Start page

685

End page

690

Subjects

Neocortex

•

Microcircuit

•

Correlations

•

Subthreshold

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LNMC  
LCN  
Available on Infoscience
November 21, 2007
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/14874
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