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research article

Sedimentation of macroscopic rigid knots and its relation to gel electrophoretic mobility of DNA knots

Weber, Cedric  
•
Carlen, Mathias
•
Dietler, Giovanni  
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2013
Scientific Reports

We address the general question of the extent to which the hydrodynamic behaviour of microscopic freely fluctuating objects can be reproduced by macrosopic rigid objects. In particular, we compare the sedimentation speeds of knotted DNA molecules undergoing gel electrophoresis to the sedimentation speeds of rigid stereolithographic models of ideal knots in both water and silicon oil. We find that the sedimentation speeds grow roughly linearly with the average crossing number of the ideal knot configurations, and that the correlation is stronger within classes of knots. This is consistent with previous observations with DNA knots in gel electrophoresis.

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Type
research article
DOI
10.1038/srep01091
Web of Science ID

WOS:000313885400003

Author(s)
Weber, Cedric  
Carlen, Mathias
Dietler, Giovanni  
Rawdon, Eric J.
Stasiak, Andrzej
Date Issued

2013

Publisher

Nature Publishing Group

Published in
Scientific Reports
Volume

3

Article Number

1091

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LPMV  
Available on Infoscience
March 28, 2013
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/90872
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