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research article

Dynamic functional connectivity to tile the spatiotemporal mosaic of brain states

Van De Ville, Dimitri  
•
Liégeois, Raphaël  
November 19, 2024
Imaging Neuroscience

Resting-state fMRI has spurred an impressive amount of methods development, among which dynamic functional connectivity (dFC) is one important branch. However, the relevance of time-varying and time-resolved features has led to debate, to which we want to bring in our viewpoint. We argue that, while statistically many dFC features extracted from resting state are contained within a sufficiently strong null model, these features can still reflect underlying neuronal activity. The use of naturalistic experimental paradigms, at the boundary between resting state and task, is essential to validate their relevance. In parallel, leveraging methods that specifically rely on sparsity is an avenue to strengthen the statistical significance of time-resolved information carried by ongoing brain activity.

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Type
research article
DOI
10.1162/imag_a_00364
Scopus ID

2-s2.0-105006980121

Author(s)
Van De Ville, Dimitri  

École Polytechnique Fédérale de Lausanne

Liégeois, Raphaël  

École Polytechnique Fédérale de Lausanne

Date Issued

2024-11-19

Published in
Imaging Neuroscience
Volume

2

Start page

1

End page

5

Subjects

brain dynamics

•

deconvolution

•

fMRI

•

functional connectivity

•

null models

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
MIPLAB  
FunderFunding(s)Grant NumberGrant URL

CIBM Center for Biomedical Imaging

Swiss National Science Foundation

205321-163376

Swiss National Centre of Competence in Research - Evolving Language

51NF40_180888

Available on Infoscience
June 11, 2025
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/251230
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