research article
Kinetic isotope effects for fast deuterium and proton exchange rates
By monitoring the effect of deuterium decoupling on the decay of transverse N-15 magnetization in D-N-15 spin pairs during multiple-refocusing echo sequences, we have determined fast D-D exchange rates k(D) and compared them with fast H-H exchange rates k(H) in tryptophan to determine the kinetic isotope effect as a function of pH and temperature.
Type
research article
Web of Science ID
WOS:000374350600032
Date Issued
2016
Publisher
Published in
Volume
18
Issue
15
Start page
10144
End page
10151
Editorial or Peer reviewed
REVIEWED
Written at
EPFL
EPFL units
Available on Infoscience
July 19, 2016
Use this identifier to reference this record