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  4. The fourth helical secondary structure of β-peptides: The (P)-28-helix of a β-hexapeptide consisting of (2R,3S)-3-amino-2-hydroxy acid residues
 
research article

The fourth helical secondary structure of β-peptides: The (P)-28-helix of a β-hexapeptide consisting of (2R,3S)-3-amino-2-hydroxy acid residues

Gademann, Karl  
•
Hane, Andreas
•
Rueping, Magnus
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2003
Angewandte Chemie International Edition

The authors report compelling evidence for the formation of a fourth type of helical secondary structure of a beta-peptide in MeOH, and this phenomenon occurs if each amino acid has a hydroxy group in the 2-position. 2D-NMR expts. of terminally-protected beta-hexapeptide I were conducted to obtain its secondary structure information.

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Type
research article
DOI
10.1002/anie.200250290
Author(s)
Gademann, Karl  
Hane, Andreas
Rueping, Magnus
Jaun, Bernhard
Seebach, Dieter
Date Issued

2003

Publisher

Wiley-VCH Verlag GmbH

Published in
Angewandte Chemie International Edition
Volume

42

Issue

13

Start page

1534

End page

1537

Subjects

amino acids

•

β-peptides

•

conformational analysis

•

peptidomimetics

•

secondary structure

Editorial or Peer reviewed

REVIEWED

Written at

OTHER

EPFL units
LSYNC  
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/235832
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