research article

Unconventional chalcogen-containing azolylidene metal complexes as potential anticancer therapeutics

Romano-deGea, Jan  
•
Sinenko, Irina L.  
•
Pânzar, Peter M. F.  
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2026
Chemical Science

Substituting a nitrogen for a chalcogen in N-heterocyclic carbenes alters the electronic and steric features of the resulting metal complexes, influencing their biological activity and creating new opportunities for metallocarbene drug candidates.

Type
research article
DOI
10.1039/d5sc05555e
Author(s)
Romano-deGea, Jan  

École Polytechnique Fédérale de Lausanne

Sinenko, Irina L.  

École Polytechnique Fédérale de Lausanne

Pânzar, Peter M. F.  

École Polytechnique Fédérale de Lausanne

Neves Vieira, Adriana

École Polytechnique Fédérale de Lausanne

Frederiksen, Lindsey E. K.  

École Polytechnique Fédérale de Lausanne

Glinkina, Kseniya  

École Polytechnique Fédérale de Lausanne

Fadaei-Tirani, Farzaneh  

École Polytechnique Fédérale de Lausanne

Scopelliti, Rosario  

École Polytechnique Fédérale de Lausanne

Kuttler, Fabien  

École Polytechnique Fédérale de Lausanne

Lau, Kelvin  orcid-logo

École Polytechnique Fédérale de Lausanne

Date Issued

2026

Publisher

Royal Society of Chemistry (RSC)

Published in
Chemical Science
Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LCOM  
ISIC-XRDSAP  
PTCB  
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FunderFunding(s)Grant NumberGrant URL

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

École Polytechnique Fédérale de Lausanne

Available on Infoscience
January 13, 2026
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/257870