Dynamic aperture is an important concept for the study of non-linear beam dynamics in circular accelerators. It describes the extent of the phase-space region where a particle's motion remains bounded over a given number of turns. Understanding the features of dynamic aperture is crucial for the design and operation of such accelerators, as it provides insights into nonlinear effects and the possibility of optimising beam lifetime. The standard approach to calculate the dynamic aperture requires numerical simulations of several initial conditions densely distributed in phase space for a sufficient number of turns to probe the time scale corresponding to machine operations. This process is very computationally intensive and practically outside the range of today's computers. In our study, we introduced a novel method to estimate dynamic aperture rapidly and accurately by utilising a Deep Neural Network model. This model was trained with simulated tracking data from the CERN Large Hadron Collider and takes into account variations in accelerator parameters such as betatron tune, chromaticity, and the strength of the Landau octupoles. To enhance its performance, we integrate the model into an innovative Active Learning framework. This framework not only enables retraining and updating of the computed model, but also facilitates efficient data generation through smart sampling. Since chaotic motion cannot be predicted, traditional tracking simulations are incorporated into the Active Learning framework to deal with the chaotic nature of some initial conditions. The results demonstrate that the use of the Active Learning framework allows faster scanning of the configuration parameters without compromising the accuracy of the dynamic aperture estimates.