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  4. Detailed classification of swimming paths in the Morris Water Maze: multiple strategies within one trial
 
research article

Detailed classification of swimming paths in the Morris Water Maze: multiple strategies within one trial

Gehring, Tiago V.
•
Luksys, Gediminas
•
Sandi, Carmen  
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2015
Sci Rep

The Morris Water Maze is a widely used task in studies of spatial learning with rodents. Classical performance measures of animals in the Morris Water Maze include the escape latency, and the cumulative distance to the platform. Other methods focus on classifying trajectory patterns to stereotypical classes representing different animal strategies. However, these approaches typically consider trajectories as a whole, and as a consequence they assign one full trajectory to one class, whereas animals often switch between these strategies, and their corresponding classes, within a single trial. To this end, we take a different approach: we look for segments of diverse animal behaviour within one trial and employ a semi-automated classification method for identifying the various strategies exhibited by the animals within a trial. Our method allows us to reveal significant and systematic differences in the exploration strategies of two animal groups (stressed, non-stressed), that would be unobserved by earlier methods

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Type
research article
DOI
10.1038/srep14562
Web of Science ID

WOS:000362081500001

Author(s)
Gehring, Tiago V.
Luksys, Gediminas
Sandi, Carmen  
Vasilaki, Eleni
Date Issued

2015

Publisher

Nature Publishing Group

Published in
Sci Rep
Volume

5

Article Number

14562

Editorial or Peer reviewed

REVIEWED

Written at

OTHER

EPFL units
LGC  
Available on Infoscience
August 27, 2015
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/117400
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