research article

Alpha-synuclein seed amplification assays: Data sharing, standardization needed for clinical use

Lashuel, Hilal A.  
•
Surmeier, D. James
•
Simuni, Tanya
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April 4, 2025
Science Advances

Alpha-synuclein seed amplification assays can improve neurodegenerative disease diagnosis and care, but widespread use depends on a framework that standardizes protocols and encourages data sharing.

Type
research article
DOI
10.1126/sciadv.adt7195
Author(s)
Lashuel, Hilal A.  

École Polytechnique Fédérale de Lausanne

Surmeier, D. James

Northwestern University

Simuni, Tanya

Northwestern University

Merchant, Kalpana

Northwestern University

Caughey, Byron

National Institute of Allergy and Infectious Diseases

Soto, Claudio
Fares, Mohamed-Bilal

ND BioSciences, Epalinges, Switzerland.

Heym, Roland G.

AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany.

Melki, Ronald
Date Issued

2025-04-04

Publisher

American Association for the Advancement of Science (AAAS)

Published in
Science Advances
Volume

11

Issue

14

Article Number

eadt7195

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LMNN  
Available on Infoscience
April 10, 2025
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/249051