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research article

Unravelling socio-motor biomarkers in schizophrenia

Slowinski, Piotr
•
Alderisio, Francesco
•
Zhai, Chao
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2017
Npj Schizophrenia

We present novel, low-cost and non-invasive potential diagnostic biomarkers of schizophrenia. They are based on the 'mirrorgame', a coordination task in which two partners are asked to mimic each other's hand movements. In particular, we use the patient's solo movement, recorded in the absence of a partner, and motion recorded during interaction with an artificial agent, a computer avatar or a humanoid robot. In order to discriminate between the patients and controls, we employ statistical learning techniques, which we apply to nonverbal synchrony and neuromotor features derived from the participants' movement data. The proposed classifier has 93% accuracy and 100% specificity. Our results provide evidence that statistical learning techniques, nonverbal movement coordination and neuromotor characteristics could form the foundation of decision support tools aiding clinicians in cases of diagnostic uncertainty.

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Type
research article
DOI
10.1038/s41537-016-0009-x
Web of Science ID

WOS:000411256500001

Author(s)
Slowinski, Piotr
Alderisio, Francesco
Zhai, Chao
Shen, Yuan
Tino, Peter
Bortolon, Catherine
Capdevielle, Delphine
Cohen, Laura
Khoramshahi, Mahdi  
Billard, Aude  orcid-logo
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Date Issued

2017

Published in
Npj Schizophrenia
Volume

3

Start page

8

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LASA  
Available on Infoscience
October 9, 2017
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/141104
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