An acoustic dimer composed of two electronically controlled electroacoustic resonators is presented with the view of exploring one-dimensional topological phenomena. Active control allows real-time manipulation of the metamaterial’s properties, including its mechanical mass, resistance, compliance, and internal coupling. The latter enables active tuning of the topological phase transition in the effective acoustic Su-Schrieffer-Heeger system. An analytical model of the unit cell as well as the electronic control scheme is provided. Band structures derived from the analytical model, the finite-element simulation, and the experimental data consistently demonstrate the realization of a tunable one-dimensional topological insulator.