Microwave-Assisted Intramolecular Suzuki-Miyaura Reaction to Macrocycle, a Concise Asymmetric Total Synthesis of Biphenomycin B

Lepine, Renaud; Zhu, Jieping

doi:10.1021/ol050949w

research article

Microwave-Assisted Intramolecular Suzuki-Miyaura Reaction to Macrocycle, a Concise Asymmetric Total Synthesis of Biphenomycin B

Lepine, Renaud

•

Zhu, Jieping

2005

Organic Letters

A concise and efficient total synthesis of biphenomycin B (I) was accomplished featuring a key microwave-assisted intramol. Suzuki-Miyaura reaction for formation of the 15-membered meta,meta-cyclophane 20. [on SciFinder (R)]