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research article

Population-Level Intervention and Information Collection in Dynamic Healthcare Policy

Cipriano, L. E.
•
Weber, Thomas A.  
2018
Health Care Management Science

We develop a general framework for optimal health policy design in a dynamic setting. We consider a hypothetical medical intervention for a cohort of patients where one parameter varies across cohorts with imperfectly observable linear dynamics. We seek to identify the optimal time to change the current health intervention policy and the optimal time to collect decision-relevant information. We formulate this problem as a discrete-time, infinite-horizon Markov decision process and we establish structural properties in terms of first and second-order monotonicity. We demonstrate that it is generally optimal to delay information acquisition until an effect on decisions is sufficiently likely. We apply this framework to the evaluation of hepatitis C virus (HCV) screening in the general population determining which birth cohorts to screen for HCV and when to collect information about HCV prevalence.

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Type
research article
DOI
10.1007/s10729-017-9415-5
Author(s)
Cipriano, L. E.
Weber, Thomas A.  
Date Issued

2018

Published in
Health Care Management Science
Volume

21

Issue

4

Start page

604

End page

631

Subjects

Medical decision making

•

Markov decision processes

•

Hepatitis C virus

•

Optimal stopping

•

Dynamic programming

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
OES  
Available on Infoscience
May 24, 2018
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/146593
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