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  4. Protein semisynthesis and total synthesis approaches to elucidate the role of Alpha-Synuclein post-translational modifications
 
doctoral thesis

Protein semisynthesis and total synthesis approaches to elucidate the role of Alpha-Synuclein post-translational modifications

Fauvet, Bruno Claude Daniel  
2014
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Type
doctoral thesis
DOI
10.5075/epfl-thesis-6187
Author(s)
Fauvet, Bruno Claude Daniel  
Advisors
Lashuel, Hilal  
Jury

Prof. C. Petersen (président) ; Prof. H. Lashuel (directeur) ; Prof. C. Becker, Prof. B. Fierz, Prof. V. Uversky (rapporteurs)

Date Issued

2014

Publisher

EPFL

Publisher place

Lausanne

Public defense year

2014-05-02

Thesis number

6187

Subjects

Parkinson’s disease (PD)

•

alpha-Synuclein (α-Syn)

•

Lewy Bodies (LB)

•

Aggregation

•

Amyloid

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Oligomers

•

Phosphorylation

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Acetylation

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c-Abl

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Autophagy

•

Solid-phase peptide synthesis (SPPS)

•

Native Chemical Ligation (NCL)

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Expressed Protein Ligation (EPL)

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Total Chemical Synthesis

•

Intein

•

Circular Dichroism (CD)

•

Nuclear Magnetic Resonance (NMR)

•

Transmission Electron Microscopy (TEM)

EPFL units
LMNN  
Faculty
SV  
School
BMI  
Doctoral School
EDNE  
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/102919
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