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  4. Compact imaging system with single-photon sensitivity and picosecond time resolution for fluorescence-guided surgery with lifetime imaging capability
 
conference paper

Compact imaging system with single-photon sensitivity and picosecond time resolution for fluorescence-guided surgery with lifetime imaging capability

Powolny, F.  
•
Bruschini, C.  
•
Dubikovskaya, E.
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Deckert, V
•
Ramanujam, N
2013
Clinical And Biomedical Spectroscopy And Imaging Iii
Conference on Clinical and Biomedical Spectroscopy and Imaging III

We present a single-photon camera for fluorescence imaging capable of providing both intensity and images, with an accuracy better than 100ps; the camera was fabricated in standard CMOS technology. As a first step towards the study of biologically relevant samples, it was used to characterize in-vitro cultured melanoma cells labeled with indocyanine green (ICG) and ICG conjugated with cyclic pentapeptide (RGDfK). The application field would be fluorescence-guided surgical oncology.

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