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  4. Palladium-Catalyzed Through-Space C(sp3)-H and C(sp2)-H Bond Activation by 1,4-Palladium Migration: Efficient Synthesis of [3,4]- Fused Oxindoles
 
research article

Palladium-Catalyzed Through-Space C(sp3)-H and C(sp2)-H Bond Activation by 1,4-Palladium Migration: Efficient Synthesis of [3,4]- Fused Oxindoles

Piou, Tiffany
•
Bunescu, Ala  
•
Wang, Qian  
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2013
Angewandte Chemie International Edition

Palladium two step: Linear anilides were converted into the title compounds in good to excellent yields through a palladium-catalyzed domino carbopalladation/1,4-palladium shift sequence. The C(sp3)-H activation involves a seven-membered palladacycle, and is chemoselective in the presence of competitive C(sp2)H bonds. DMA=N,N-dimethylacetamide, OPiv=pivalate.

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Type
research article
DOI
10.1002/anie.201306532
Web of Science ID

WOS:000326807900037

Author(s)
Piou, Tiffany
Bunescu, Ala  
Wang, Qian  
Neuville, Luc
Zhu, Jieping  
Date Issued

2013

Publisher

Wiley-Blackwell

Published in
Angewandte Chemie International Edition
Volume

52

Issue

47

Start page

12385

End page

12389

Subjects

C-H activation

•

heterocycles

•

palladium

•

chemoselectivity

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LSPN  
Available on Infoscience
November 13, 2013
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/96993
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