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research article

Adaptive phase correction of diffusion-weighted images

Pizzolato, Marco  
•
Gilbert, Guillaume
•
Thiran, Jean-Philippe  
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February 1, 2020
Neuroimage

Phase correction (PC) is a preprocessing technique that exploits the phase of images acquired in Magnetic Resonance Imaging (MRI) to obtain real-valued images containing tissue contrast with additive Gaussian noise, as opposed to magnitude images which follow a non-Gaussian distribution, e.g. Rician. PC finds its natural application to diffusion-weighted images (DWIs) due to their inherent low signal-to-noise ratio and consequent non-Gaussianity that induces a signal overestimation bias that propagates to the calculated diffusion indices. PC effectiveness depends upon the quality of the phase estimation, which is often performed via a regularization procedure. We show that a suboptimal regularization can produce alterations of the true image contrast in the real-valued phase-corrected images. We propose adaptive phase correction (APC), a method where the phase is estimated by using MRI noise information to perform a complex-valued image regularization that accounts for the local variance of the noise. We show, on synthetic and acquired data, that APC leads to phase-corrected real-valued DWIs that present a reduced number of alterations and a reduced bias. The substantial absence of parameters for which human input is required favors a straightforward integration of APC in MRI processing pipelines.

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Type
research article
DOI
10.1016/j.neuroimage.2019.116274
Web of Science ID

WOS:000507987000001

Author(s)
Pizzolato, Marco  
Gilbert, Guillaume
Thiran, Jean-Philippe  
Descoteaux, Maxime
Deriche, Rachid
Date Issued

2020-02-01

Published in
Neuroimage
Volume

206

Article Number

116274

Subjects

Neurosciences

•

Neuroimaging

•

Radiology, Nuclear Medicine & Medical Imaging

•

Neurosciences & Neurology

•

phase correction

•

phase estimation

•

oriented laplacian

•

diffusion mri

•

rician noise

•

magnetic-resonance images

•

to-noise ratio

•

mr-images

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fourier reconstruction

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anisotropic diffusion

•

map-mri

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tensor

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regularization

•

framework

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LTS5  
Available on Infoscience
March 3, 2020
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/166867
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