This paper explores the transdisciplinary methodology crafted by a collaborative research team of architects, civil engineers, and material scientists, from EPFL (École Polytechnique Fédérale de Lausanne) and UFBA (Federal University of Bahia), in partnership with the local NGO (Grupo Sofonias), to promote sustainable social housing solutions in Nicaragua. By employing Textile Reinforced Concrete (TRC) and Limestone Calcined Clay Cement (LC 3), the research adopts a community-centered approach that emphasizes iterative, hands-on experimentation. The framework includes field research, laboratory testing, and prototyping across four key domains: social context, architectural design, material science, and structural response. Each domain contributes to the goal of advancing at accessible and resilient light housing solutions that address the local needs and environmental conditions in Latin America.