Availability of Visible Human Dataset (VHD) has provided numerous possibilities for its exploitation in both medical applications and 3D animation. We present our interactive tools which enable extraction of surfaces for different organs, including bones, muscles, fascia, and skin, from the VHD. The reconstructed surfaces then are used for defining the interrelationship of organs, a process we refer to as topological modeling. A database is constructed, which encapsulates structural, topological, mechanical and other relevant information about organs. A 3D interactive tool enables the building and editing of this database. Such a database can later be used for different applications in fields such as medicine, sports, education, and entertainment