Preparation and NMR structure of the cyclo-β-tripeptide [β3-HGlu] in aqueous solution. A new class of enterobactin-type C3-symmetrical ligands?
By exploiting the solubilizing effect of LiCl on peptides in THF, the water-sol. title compd. could be prepd., and its structure was detd. by NMR. Structural similarities and differences between the trilactam ring of [beta3-HGlu]3 and the corresponding trilactone ring, such as that of enterobactin, are discussed, and structures are proposed that should be able to serve as tridentate or trivalent ligands for metal centers.
Record created on 2006-11-22, modified on 2016-08-08