Loading...
research article
Peptide folding: when simulation meets experiment
Mol. dynamics simulation studies on the folding of beta-peptides H-beta3-HVal-beta3-HAla-beta3-HLeu-(S,S)-beta3-HAla(alphaMe)-beta3-HVal-beta3-HAla-beta3-HLeu-OH and H-beta2-HVal-beta3-HAla-beta2-HLeu-beta3-HVal-beta2-HAla-beta3-HLeu-OH were carried out. Despite the small differences in sequence between the two peptides studied, the simulations correctly predict a left-handed 31-helical fold for the beta-heptapeptide and a right-handed helical fold for the beta-hexapeptide.
Loading...
Name
005 ACIE 1999, 38, 236.pdf
Access type
restricted
Size
213.69 KB
Format
Adobe PDF
Checksum (MD5)
ea2ccfa04f8ac1b1e03cb2924a06ab6c