Synchrotron microangiography with no contrast agent
Coherent x-rays from synchrotron sources are increasingly used in non-conventional radiological techniques ('phase-contrast' radiology). Our experiments demonstrate that by using white (unmonochromatic) radiation and a time-resolving system, it is possible to image microscopic details of moving blood vessels in different live animals without using any contrast agent. The images have excellent contrast plus unprecedented spatial resolution for microangiography (< 10 mum). This result is likely to impact many different areas of biological and medical research and of diagnostic radiology.
WOS:000220391400003
2004
49
4
501
508
Acad Sinica, Inst Phys, Taipei, Taiwan. Pohang Univ Sci & Technol, Dept Mat Sci & Engn, Pohang, South Korea. EPFL, Fac Sci Base, CH-1015 Lausanne, Switzerland. Yonsei Univ, Coll Med, Med Res Ctr, Seoul, South Korea. Hwu, Y, Acad Sinica, Inst Phys, 128 Acad Rd, Taipei, Taiwan.
ISI Document Delivery No.: 805UO
REVIEWED