Myosin assembly: the power of multiubiquitylation
Ubiquitylation provides a means of targeting substrate proteins for degradation by the proteasome. Novel findings in C. elegans (Hoppe et al., 2004, this issue of Cell) establish that two ubiquitin-ligases team up to multiubiquitylate the myosin chaperone UNC-45, suggesting a novel link between regulated protein degradation and myosin assembly.
- URL: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15294151
ISREC (Swiss Institute for Experimental Cancer Research), 155, ch. des Boveresses, CH-1066 Epalinges/Lausanne.
Record created on 2006-08-24, modified on 2016-08-08