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research article

Nuclear envelope: torn apart at mitosis

Gönczy, P.  
2002
Current Biology

The findings of two recent studies suggest a novel mechanism for nuclear envelope breakdown in which cytoplasmic dynein anchored on the outside of the nucleus generates tension, thus triggering tearing of the nuclear envelope.

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Type
research article
DOI
10.1016/S0960-9822(02)00781-9
PubMed ID

11937039

Author(s)
Gönczy, P.  
Date Issued

2002

Published in
Current Biology
Volume

12

Issue

7

Start page

R242

End page

R244

Subjects

Animals

•

CDC2 Protein Kinase/metabolism

•

Dynein ATPase/*metabolism

•

Humans

•

Lamins

•

Microtubule-Associated Proteins/*metabolism

•

Microtubules/metabolism/physiology

•

Mitosis/*physiology

•

Nuclear Envelope/metabolism/*physiology

•

Nuclear Proteins/*metabolism

Note

ISREC (Swiss Institute for Experimental Cancer Research), 155, ch. des Boveresses, CH-1066, Epalinges/Lausanne, Switzerland. Pierre.Gönczy@isrec.unil.ch

Journal Article

Review

Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
UPGON  
Available on Infoscience
August 24, 2006
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/233778
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