Biphasic constitutive laws for biological interface evolution

A model of tissue differentiation at the bone-implant interface is proposed. The basic hypothesis of the model is that the mechanical environment determines the tissue differentiation. The stimulus chosen is related to the bone-implant micromotions. Equations governing the evolution of the interfacial tissue are proposed and combined with a finite element code to determine the evolution of the fibrous tissue around prostheses. The model is applied to the case of an idealized hip prosthesis.


Published in:
Biomech Model Mechanobiol, 1, 4, 239-49
Year:
2003
Keywords:
Note:
LRO, Bat. AAB, Laboratory of Orthopedic Research, EPFL, 1015 Lausanne, Switzerland. philippe.buechler@epfl.ch, 1617-7959 (Print), Evaluation Studies, Journal Article
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 Record created 2006-07-25, last modified 2018-03-17

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