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research article
Les étapes du développement du pancreas: des pistes pour le traitement du diabète [Different steps in pancreas development: toward diabetic therapies?]
The formation of the pancreas from the endoderm layer takes place in different steps including the specification of the precursor territory, the outgrowth of pancreas buds, the differentiation of exocrine and endocrine cells, and the migration of endocrine cells which leads to islet formation. These processes are controlled by mesoderm-endoderm interactions and specific induction of a set of transcription factors. Deciphering the cascade of genes involved in beta-cell induction will provide essential tools to engineer cells for diabetes therapy.
Type
research article
Authors
Publication date
2002
Published in
Volume
18
Issue
4
Start page
467
End page
473
Note
Article
M S-MED SCI
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
June 13, 2006
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