Journal article

Enzymic ester hydrolysis in liquid two-phase systems for the preparation of L-phenylalanine

L-Phenylalanine was produced from phenylalanine Pr esters by chymotrypsin in 2-phase systems (org. phase using iso-Bu Me ketone and aq. phase). Control of pH during the enzymic reaction was crit. The reaction was carried out in a batch fermentor or a fixed-bed reactor. It was also possible to use chymotrypsin immobilized in 3-aminopropyltriethoxysilane and(or) glutaraldehyde-activated silica gel. [on SciFinder (R)]

    Keywords: phenylalanine ester hydrolysis chymotrypsin


    CAN 111:55734


    Fermentation and Bioindustrial Chemistry

    Inst. Chem. Eng.,Swiss Fed. Inst. Technol.,Lausanne,Switz.



    written in English.

    121661-48-1 Role: RCT (Reactant), RACT (Reactant or reagent) (hydrolysis of, by chymotrypsin in liq. 2-phase system); 9004-07-3 (Chymotrypsin) Role: RCT (Reactant), RACT (Reactant or reagent) (phenylalanine ester hydrolysis by, in liq. 2-phase system); 63-91-2P (L-Phenylalanine) Role: PREP (Preparation) (prepn. of, by enzymic ester hydrolysis in liq. 2-phase system)


    • LGRC-ARTICLE-1988-001

    Record created on 2006-04-18, modified on 2016-08-08


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