About bases and superbases

A review with 26 refs. on the authors work on metalation by bases and superbases. BuLi requires activation to become capable of abstracting a proton from weakly acidic hydrocarbons like cyclopropanes, simple olefins, or arenes. The addn. of stoichiometric amts. of KOCMe3 is a most effective means of enhancing the rate of a H/metal exchange. Superbasic alkyllithium/K alcoholate mixts. are endowed not only with an unsurpassed reactivity but also with a surprisingly high selectivity as evidenced by series of optionally site-selective arene metalations. [on SciFinder (R)]


Published in:
Chimia, 50, 12, 650-652
Year:
1996
Keywords:
Note:
CAN 126:88904
22-0
Physical Organic Chemistry
Institut Chimie Organique,Universite Lausanne,Lausanne,Switz.
Journal; General Review
0009-4293
written in English.
Laboratories:




 Record created 2006-03-03, last modified 2018-01-27


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