An efficient synthesis of (2S,3R)- and (2S,3S)-sphingosine
A straightforward sequence of reactions allowed the conversion of D-(+)-mannose and D-(+)-ribono-1,4-lactone into erythro-(2S,3R)- and threo-(2S,3S)-sphingosine, resp. [on SciFinder (R)]
1985
11
1715
1718
CAN 105:97227
26-9
Biomolecules and Their Synthetic Analogs
Inst. Chim. Org.,Univ. Lausanne,Lausanne,Switz.
Journal
written in English.
3458-28-4 Role: PROC (Process) (conversion of, to sphingosine); 5336-08-3P; 102854-88-6P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of); 765-09-3P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of, from mannose); 25695-95-8P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of, from ribonolactone); 20689-02-5P; 20689-03-6P; 54469-08-8P; 72050-19-2P; 72050-22-7P; 72050-23-8P; 79940-48-0P; 86436-80-8P; 102854-75-1P; 102854-76-2P; 102854-77-3P; 102854-78-4P; 102854-79-5P; 102854-80-8P; 102854-81-9P; 102854-82-0P; 102854-83-1P; 102854-84-2P; 102854-85-3P; 102854-86-4P; 102854-87-5P; 102919-04-0P; 102919-05-1P; 102919-06-2P; 102919-07-3P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of, intermediate in synthesis of sphingosine); 765-09-3 Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, in synthesis of sphingosine)
REVIEWED