Base-induced elimination reactions. VII. Hydroxide-promoted elimination reactions: alkyl halides as substrates
1977
Résumé
HCl and HBr were easily abstracted from secondary and tertiary alkyl halides by KOH in tetraglyme, but primary alkyl halides yielded approx. equal amts. of elimination and substitution products (alkenes and alcs. and/or ethers). However, the addn. of catalytic amts. of Me3N favored dehydrohalogenation via quaternary ammonium salt intermediates. [on SciFinder (R)]
Détails
Titre
Base-induced elimination reactions. VII. Hydroxide-promoted elimination reactions: alkyl halides as substrates
Auteur(s)
Schlosser, Manfred ; Tarchini, Claudio
Publié dans
Helvetica Chimica Acta
Volume
60
Numéro
8
Pages
3060-3068
Date
1977
ISSN
0018-019X
Mots-clés (libres)
Note
CAN 88:89011
23-3
Aliphatic Compounds
Inst. Chim. Org.,Univ. Lausanne,Lausanne,Switz.
Journal
written in English.
75-50-3; 75-57-0; 506-59-2; 593-81-7; 5882-44-0; 15925-18-5; 16645-06-0 Role: CAT (Catalyst use), USES (Uses) (catalysts, for dehydrohalogenation of alkyl halides); 111-85-3; 628-61-5; 931-78-2 Role: RCT (Reactant), RACT (Reactant or reagent) (dehydrochlorination of, by potassium hydroxide and alkoxides); 111-83-1; 557-35-7 Role: RCT (Reactant), RACT (Reactant or reagent) (dehydrochlorination of, with potassium hydroxide and alkoxides); 2083-68-3P; 32359-06-1P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and decompn. of); 5706-90-1P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and stereoselective dehydrochlorination of); 5706-91-2P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of); 865-33-8; 865-47-4; 917-58-8; 1310-58-3 Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with alkyl halides); 143-24-8 Role: RCT (Reactant), RACT (Reactant or reagent) (solvent, for dehydrohalogenation of alkyl halides by potassium hydroxide)
23-3
Aliphatic Compounds
Inst. Chim. Org.,Univ. Lausanne,Lausanne,Switz.
Journal
written in English.
75-50-3; 75-57-0; 506-59-2; 593-81-7; 5882-44-0; 15925-18-5; 16645-06-0 Role: CAT (Catalyst use), USES (Uses) (catalysts, for dehydrohalogenation of alkyl halides); 111-85-3; 628-61-5; 931-78-2 Role: RCT (Reactant), RACT (Reactant or reagent) (dehydrochlorination of, by potassium hydroxide and alkoxides); 111-83-1; 557-35-7 Role: RCT (Reactant), RACT (Reactant or reagent) (dehydrochlorination of, with potassium hydroxide and alkoxides); 2083-68-3P; 32359-06-1P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and decompn. of); 5706-90-1P Role: RCT (Reactant), SPN (Synthetic preparation), PREP (Preparation), RACT (Reactant or reagent) (prepn. and stereoselective dehydrochlorination of); 5706-91-2P Role: SPN (Synthetic preparation), PREP (Preparation) (prepn. of); 865-33-8; 865-47-4; 917-58-8; 1310-58-3 Role: RCT (Reactant), RACT (Reactant or reagent) (reaction of, with alkyl halides); 143-24-8 Role: RCT (Reactant), RACT (Reactant or reagent) (solvent, for dehydrohalogenation of alkyl halides by potassium hydroxide)
Laboratoires
LSCO
Le document apparaît dans
Production scientifique et compétences > SB - Faculté des sciences de base > SB Archives > LSCO - Laboratoire de synthèse organique et catalyse
Publications validées par des pairs
Travail produit à l'EPFL
Articles de journaux
Publié
Publications validées par des pairs
Travail produit à l'EPFL
Articles de journaux
Publié
Date de création de la notice
2006-03-03