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research article
Adding value to fusion proteins through covalent labeling
A review. Recombinant proteins are often expressed with an addnl. polypeptide the role of which is to aid purifn., detection, or functional studies. Recently, the role of these tags has been extended to mediate the labeling of the protein of interest with chem. diverse compds. These approaches are of importance for protein science as they allow proteins to be equipped with properties that cannot be genetically encoded and also enable the use of a single fusion protein for several different applications. Several new approaches have been developed for the covalent labeling of fusion proteins both in living cells and in vitro. [on SciFinder (R)]
Type
research article
Web of Science ID
WOS:000231659000014
Authors
Publication date
2005
Published in
Volume
16
Issue
4
Start page
453
End page
458
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
February 27, 2006
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