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research article
Triple helix binding of oligodeoxyribonucleotides containing 8-oxo-2'-deoxyadenosine
Formation of a triple helix between an oligodeoxyribonucleotide contg. 8-oxo-2'-deoxyadenosine and a DNA duplex target was studied as a function of pH. Above pH 7.4, the triple helix with the 8-oxo-2'-deoxyadenosine was more stable than the complex with an analogous oligodeoxyribonucleotide contg. deoxycytidine instead of 8-oxo-2'-deoxyadenosine.
Type
research article
Authors
Publication date
1993
Published in
Volume
12
Issue
2
Start page
237
End page
43
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
February 27, 2006
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