Infoscience

Journal article

Triple helix binding of oligodeoxyribonucleotides containing 8-oxo-2'-deoxyadenosine

Formation of a triple helix between an oligodeoxyribonucleotide contg. 8-oxo-2'-deoxyadenosine and a DNA duplex target was studied as a function of pH. Above pH 7.4, the triple helix with the 8-oxo-2'-deoxyadenosine was more stable than the complex with an analogous oligodeoxyribonucleotide contg. deoxycytidine instead of 8-oxo-2'-deoxyadenosine. [on SciFinder (R)]

    Reference

    • LIP-ARTICLE-1993-001

    Record created on 2006-02-27, modified on 2016-08-08

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