Membrane-spanning bent helix modeling receptor protein channel function

Dansyl-(Ala-Aib-Ala-Aib-Ala)3-Pro-Ala-Aib-Ala-Aib-Ala-Trp-OMe [(I), where Aib is a-aminoisobutryate] is a bent a-helical peptide which displays ion channel activity characteristic of the nicotinic acetylcholine receptor. The membrane organization, side-chain and backbone motions, and voltage dependence of the I ion channel are discussed. [on SciFinder (R)]


Published in:
Peptides : chemistry, structure and biology, 658-60
Presented at:
Eleventh American Peptide Symposium, La Jolla, California, U.S.A., July 9-14, 1989
Year:
1990
Laboratories:




 Record created 2006-02-27, last modified 2018-03-17


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