The structure of polypeptides and membrane proteins involved in pore formation and transport processes

The conformations of melittin, porin, and lactose permease reconstituted in liposomal membranes were investigated by Raman spectroscopy, and the folding of membrane domains was predicted. These data resulted in consistent models for the insertion of the proteins in lipid bilayers and for the formation of hydrophilic channels and pores from regions of amphipathic secondary structure. [on SciFinder (R)]


Published in:
Spectroscopy of biological molecules, 259-64
Presented at:
First European conference on the spectroscopy of biological molecules, Reims, 1985
Year:
1985
Laboratories:




 Record created 2006-02-27, last modified 2018-03-17


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