Binding of organoruthenium anticancer drugs to DNA

Organoruthenium compds. have emerged as promising novel anticancer agents but very little is known about their mol. mechanism of action. Here, we present classical and mixed QM/MM first-principles MD simulations of two ruthenium(II) compds. and their binding to DNA. [on SciFinder (R)]


Published in:
Abstracts of Papers, 229th ACS National Meeting, San Diego, CA, United States, March 13-17, 2005, COMP-333
Year:
2005
Laboratories:




 Record created 2006-02-27, last modified 2018-03-17


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