Journal article

The influence of pressure and temperature of compressed CO2 on the survival of yeast cells

To study the potential use of supercrit. CO2 extn. for the recovery of products from yeast cell cultures, the effects of CO2 on different yeast strains over a range of pressures and temps. have been examd. Viability was shown to be dependent on temp. and dissolved CO2 concn., and can be described by a sigmoidal (S-shaped) curve. Cell death was mainly due to an 'anesthesia effect' rather than cell rupture. Important differences in sensitivity were obsd. for the strains studied, with the following order of resistance: Kluyveromyces fragilis>Saccharomyces cerevisiae>Candida utilis. [on SciFinder (R)]


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