Protecting groups for the synthesis of ribonucleic acids

A review, with 17 refs. Methods for the regioselective introduction of alkoxymethyl-groups into the 2'-O-position of 5'-O-dimethoxytritylated, nucleobase-protected ribonucleosides and for the N-alkyloxycarbonylation of adenine and guanine nucleosides were developed. These methods were used for the prepn. of RNA-phosphoramidites carrying novel fluoride- and photolabile sugar and nucleobase protecting groups. [on SciFinder (R)]


Published in:
Chimia, 55, 4, 320-324
Year:
2001
Laboratories:




 Record created 2006-02-27, last modified 2018-01-27


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